Origins of PROMIS
Literature Review Items |
Archival Data Analysis | Item Classification
In May 2002, the Director of the National
Institutes of Health (NIH) convened a series of meetings to chart a "roadmap"
for medical research in the 21st century. From those meetings the NIH Common Fund was created to address significant public
health problems facing biomedical research that no single Institute could tackle
alone but that by combining resources, the NIH institutes together could accelerate
the progress of medical research. The ultimate goal of the NIH Common Fund is to catalyze changes necessary for transforming
new scientific knowledge into tangible benefits for people in three areas: New Pathways
to Discovery, Research Teams of the Future, and Re–engineering the Clinical
One of the programs within the Re–engineering the Clinical Research Enterprise
initiative involved the Dynamic Assessment of Patient–Reported Chronic Disease
Outcomes. In support of this initiative, in September 2004, the NIH initiated a
multicenter cooperative group, referred to as the Patient Reported Outcomes Measurement
Information System (PROMIS).
Six primary research sites and a statistical coordinating center were funded in
the 2004–2009 round of PROMIS grants.
The foundational work of this dedicated set of researchers provides the scientific
basis included in this section and upon which PROMIS continues to build.
Accomplishments of the PROMIS Network during the first round of included:
- Established domain framework and selection of candidate items for an initial set
of adult and pediatric item banks.
- Established and administered the PROMIS core questionnaire in paper and electronic
forms to a large sample of individuals suffering from a variety of chronic diseases.
Analyzed and used collected data to calibrate the item sets to build the PROMIS
- Built an electronic Web–based resource for administering computerized adaptive
tests, collecting self–report data, and reporting instant health assessments.
- Conducted feasibility studies to evaluate the utility of PROMIS and promote widespread
use of the instrument for clinical research and clinical care.
- Supported both independent and network–wide research projects that will benefit
- Developed a plan to establish a public&ndashprivate partnership to sustain the repository,
ensure scientific excellence, improve future data collection activities, add new
domains and items to the system, test and adapt the system for new populations,
maintain the system in the public domain, and extend the application of the system
for clinical research and practice.