University of Washington (Amtmann, PI)


Grant Number: 1U01AR052171-01
Project Title: UW Center on Outcomes Research in Rehabilitation (UWCORR)
PI Name, Title and Contact Information: Dagmar Amtmann, PhD, Principal Investigator, Research Associate Professor, Department of Rehabilitation of Medicine, University of Washington
Other Key Personnel: Kurt L. Johnson, PhD, Co-Principal Investigator
Mark P. Jensen, PhD, Co-Investigator
George H. Kraft, MD, Co-Investigator
Kathryn Yorkston, PhD, Co-Investigator
Karon F. Cook, PhD, Co-Investigator/Psychometrician
John F. McLaughlin, MD, Co-Investigator
Web Site: http://uwcorr.washington.edu

Abstract:

The University of Washington Center on Outcomes Research in Rehabilitation (UWCORR) has the broad, long–term objective of facilitating clinical research in pain and fatigue by developing psychometrically validated measures of pain and fatigue in children and adults with disabilities. In addition, UWCORR aims to increase the scientific understanding of pain and fatigue in children and adults with disabilities.

The independent research project conducted two studies. Study 1 was a cross–sectional study of pain and fatigue and their impact on important outcome measures (participation, depression, and disability level) in 1,200 adults and children. Study 2 was a prospective, longitudinal study with 600 adults and children measured on the set of health outcomes, symptoms and quality of life indicators over six 4–month intervals. In addition to examining how pain, fatigue, and emotional distress affect quality of life, the data were used to evaluate psychometric properties of selected measures in people with multiple sclerosis and spinal cord injury and to develop new instruments for measuring important domains in medical rehabilitation. UWCORR lead the development of PROMIS pain item banks, developed physical function item bank appropriate for users of mobility aids, conducted usability and accessibility studies to ensure that the PROMIS Assessment Center is usable by participants with disabilities, including those who use assistive technology, and conducted a validation study of PROMIS measures in people with back pain.

For questions concerning the role of the University of Washington in the PROMIS network, please contact Dagmar Amtmann, PhD at uwcorr@u.washington.edu. For more information about the PROMIS network, go to http://www.nihpromis.org.